Epitalon
Mechanism
Four amino acids, Ala-Glu-Asp-Gly, that's the entire compound, and Khavinson's whole claim is that it can flip telomerase on in somatic cells while also nudging your pineal gland to put out more melatonin. Small peptide. Big claim.
Key Benefit
Russian studies report telomere elongation in cell cultures and improved circadian rhythm. Animal studies show lifespan extension in rodents.
Evidence Base
Nearly everything on this comes out of Russian literature, the Khavinson group specifically. No Western peer-reviewed human trials exist, none. The animal lifespan data is genuinely interesting. The methodology behind it? Still debated.
Route & Rationale
Subcutaneous injection (cycled). Small peptide. SC delivery standard. Protocols are typically short cycles (10–20 days) repeated every 4–6 months.
Interactions
No known drug interactions. Theoretical melatonin potentiation. Monitor sleep-wake patterns.
Regulatory Status
Not FDA-approved. It came off the FDA's Category 2 list in April 2026, with a PCAC review scheduled for July 2026.
For information and research purposes only. This is not medical advice and not a recommendation to use this substance. Discuss anything here with your healthcare provider.