Mechanism
A lab-built version of a tuftsin fragment, that little piece of immunoglobulin G, going to work on serotonin, dopamine, and BDNF all at once. It calms anxiety down without knocking you out and without hooking you, which is the part that gets people's attention.
Key Benefit
Approved in Russia for generalized anxiety and neurasthenia. Improves cognitive function under stress. Also shows immune-modulating properties.
Evidence Base
Approved in Russia, through Roszdravnadzor, their regulatory body. Multiple Russian clinical studies back it. The West? Barely looked at it yet.
Route & Rationale
Intranasal. Intranasal delivery crosses the blood-brain barrier effectively for CNS targets while avoiding hepatic first-pass.
Interactions
No significant known interactions. Theoretically may potentiate other anxiolytics.
Regulatory Status
Not FDA-approved here. Approved in Russia. It came off the FDA's Category 2 list in April 2026, with a PCAC review lined up for July 2026.
For information and research purposes only. This is not medical advice and not a recommendation to use this substance. Discuss anything here with your healthcare provider.
